Effects of Perchlorate in Amphibians
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The colloidal thyroxine (T4) ring as a novel biomarker of perchlorate exposure in the African clawed frog Xenopus laevis.
The purpose of this study was to determine if changes in colloidal thyroxine (T(4)) immunoreactivity can be used as a biomarker of perchlorate exposure in amphibian thyroid tissue. Larval African clawed frogs (Xenopus laevis) were exposed to 0, 1, 8, 93, and 1131 microg perchlorate/l for 38 and 69 days to cover the normal period of larval development and metamorphosis. The results of this study...
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The relative sensitivity of amphibians to chemicals in the environment, including plant protection product active substances, is the subject of ongoing scientific debate. The objective of this study was to compare systematically the relative sensitivity of amphibians and fish to chemicals. Acute and chronic toxicity data were obtained from the U.S. Environmental Protection Agency (U.S. EPA) ECO...
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Simultaneous thermal analysis (STA) method has been applied to study decomposition reactions of AP under a flowing nitrogen atmosphere and static air. Results obtained indicate that a phase transformation occurs prior to the decomposition reaction. Decomposition takes place exothermally in two stages, first stage of decomposition could be suppressed by the controlled heating programme. Addi...
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Ammonium perchlorate particles have been dried in a laboratory spouted bed dryer (screen-bottomed type) which is categorized as a fluidized bed dryer. The solid particles obtained in this process of drying were semi-porous and known as the group D of Geldart classification. The variations of moisture content with resident time, the effects of bed height on the pressure dro...
متن کاملInhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
Thyroid gland explant cultures from prometamorphic Xenopus laevis tadpoles were evaluated for their utility in assessing chemicals for thyroid hormone (TH) synthesis disruption. The response of cultured thyroid glands to bovine thyroid stimulating hormone (bTSH) and the TH synthesis inhibitors methimazole, 6-propylthiouracil, and perchlorate was determined. Thyroid glands continuously exposed f...
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تاریخ انتشار 2006